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Non-melanoma skin cancer is a global public health issue. With an ever-increasing, and ageing, world population coupled with increasing numbers of immunosuppressed individuals the number of patients continues to rise. The head and neck is overwhelmingly the most frequent location for the development of a non-melanoma skin cancer and as such challenges the clinician with its complex anatomy. The importance of maintaining the aesthetics of the face and the function of the anatomy cannot be overstated, yet ultimately it is always the aim of curing a patient with the minimum of morbidity that clinicians strive for. However, the spectrum of presentations and subsequent management varies widely, ranging from patients with the ubiquitous low-risk mid-face basal cell carcinoma to those diagnosed with relatively uncommon but potentially life-threatening high-risk squamous cell carcinomas (e.g. involving metastatic lymph nodes or with perineural invasion present) and Merkel cell carcinomas.

Oncology. Neoplasms --- oncologie

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This volume is the product of the author's long experience with melanomas and sarcomas and to a lesser but significant degree with upper gastrointestinal cancers, colorectal and breast cancers. As such, it offers a “hands-on” practical guide to approaching complex soft-tissue tumors and for performing more extensive tumor resections based on over 40 years of surgical experience. It provides important details about the positioning of patients, incision types, and exposure which can be of paramount importance in the resection of certain tumors. The book contains important general surgical principles for approaching tumors in a variety of locations but also offers the detail necessary for the safe and oncologically sound resection of these malignancies. Moreover, this operative atlas contains specific information for procedures which are not as commonly encountered in surgical training, but can be invaluable in the management of patients with locally aggressive tumors, such as hemipelvectomy and its variants, sacral resections, and forequarter amputation. Through the use of multiple detailed illustrations, Atlas of Operative Procedures in Surgical Oncology serves as a valuable resource to the general surgeon or surgical oncologist in the operative management of patients with cancer in the abdomen, retroperitoneum, pelvis or extremities. .

Oncology. Neoplasms --- oncologie

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This book provides detailed, comprehensive and illustrative content to the surgical community in the areas of foregut oncologic surgery. The text contains an in-depth review of all surgical aspects of oncologic diseases involving the stomach and esophagus. The main focus is on the minimally invasive techniques including potential complications and their management. The text also includes an online link to the videos for all minimally invasive foregut surgical procedures, including animation content which provide a more comprehensive learning experience. Minimally Invasive Foregut Surgery for Malignancy: Principles and Practice is structured in a way that makes it useful at every level of training and will be of great utility to practicing surgeons, fellows in surgical subspecialty training and surgical residents.

Oncology. Neoplasms --- Surgery --- oncologie --- chirurgie

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This volume provides a comprehensive perspective on surgical oncologic diseases that are relevant to those who have an interest in surgical oncology. Its purpose is to distill a voluminous amount of information to readers so they will have the opportunity to apply relevant information and knowledge to their particular needs. Each chapter is written by experts in their field who provide concise and in-depth information on their topic and supply references to key articles. Illustrations, diagrams, and photographs are included to assist the visual learners. Each chapter begins with bulleted key points to focus the readers on the material that will be covered and concludes with an appendix that summarizes the salient points. This unique set-up can be used as a tool to quickly review the topic at hand. The text also includes a set of short questions and answers at the end of each chapter to reinforce the salient points. Surgical Oncology: A Practical and Comprehensive Approach is a valuable resource for Medical students, surgical oncology fellows, general surgeons, and educators.

Oncology. Neoplasms --- Surgery --- oncologie --- chirurgie

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Cells are by nature compelled to live in groups. They develop dependence over signaling cues received from their microenvironment, in particular from other cells, whether of their own “kind” or of a different type. Therefore, communicating with these cells is a critical aspect of their behavior and fate, as they live and die normally or as they undergo disease-related pathological changes, with dramatic repercussions. In this book, we have asked expert researchers in the field of Intercellular Communication in Cancer to provide chapters on different aspects of interaction between neighboring cells, in the context of cancer diseases. We have specifically focused our efforts on membrane-to-membrane contact-based rather than growth factors-mediated modes of intercellular communications. The contributing authors provide an extensive overview of their respective area of specialization, with an in-depth discussion of the molecular mechanisms of cell-cell interactions, the impact on tumor progression and response to therapies, as well as the cancer diagnostic value of this scientific information. This book aims to introduce essential aspects of the normal and pathological cellular fate and homeostasis to both scientists and clinicians, and also to provide established researchers with an update on the novelties and future directions this expanding field is witnessing.

Biology --- Oncology. Neoplasms --- biologie --- oncologie